Fas/FasL gene polymorphism in patients with Hashimoto's thyroiditis in Turkish population


ERDOĞAN M. , Kulaksizoglu M., GANİDAĞLI S., BERDELİ A.

JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, cilt.40, ss.77-82, 2017 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 40 Konu: 1
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1007/s40618-016-0534-5
  • Dergi Adı: JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
  • Sayfa Sayısı: ss.77-82

Özet

Objective Hashimoto's disease is a polygenic disorder with complex etiopathogenesis. Apoptosis is proposed as one of its mechanisms. The Fas/Fas ligand cascade represents a major pathway initiating apoptosis. This study aims to evaluate the influence of Fas and FasL gene polymorphism in Hashimoto's thyroiditis in Turkish population.