Corneal permeation studies of everolimus microemulsion

Baspinar Y. , Bertelmann E., Pleyer U., Buech G., Siebenbrodt I., Borchert H.

JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS, vol.24, no.4, pp.399-402, 2008 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 24 Issue: 4
  • Publication Date: 2008
  • Doi Number: 10.1089/jop.2007.0088
  • Title of Journal : JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS
  • Page Numbers: pp.399-402

Abstract

Purpose: To prevent corneal-graft rejection, the topical application of an immunosuppressive drug is an alternative to the systemic application of immunosuppressive drugs or corticosteroids, which may have adverse side effects. The aim of this study was to determine the permeation rate of everolimus through freshly isolated pig cornea (ex vivo).