Evaluation of gingival crevicular fluid cyclophilin a and extracellular matrix metalloproteinase inducer levels in different periodontal diseases

Eren G. , Turkoglu O. , Atmaca H., Atilla G.

ARCHIVES OF ORAL BIOLOGY, cilt.68, ss.162-166, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Objective: Cyclophilin A (CypA) is able to regulate inflammatory responses and matrix metalloproteinase production via its interaction with extracellular matrix metalloproteinase inducer (EMMPRIN). EMMPRIN is the cell surface receptor of CypA. The aim of the present study was to evaluate the gingival crevicular fluid (GCF) CypA and EMMPRIN levels in patients with chronic periodontitis (CP), generalized aggressive periodontitis (G-AgP) and periodontally healthy controls.