Cycloartane-type glycosides from Astragalus brachycalyx FISCHER and their effects on cytokine release and hemolysis


ASLANIPOUR B., GÜLCEMAL D. , NALBANTSOY A. , YUSUFOGLU H., Bedir E.

PHYTOCHEMISTRY LETTERS, cilt.21, ss.66-73, 2017 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 21
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1016/j.phytol.2017.05.028
  • Dergi Adı: PHYTOCHEMISTRY LETTERS
  • Sayfa Sayıları: ss.66-73

Özet

Two new tridesmosidic cycloartane-type triterpene glycosides (1 and 2) were isolated from the methanolic extract of the roots of Astragalus brachycalyx FISCHER (A. brachycalyx) along with ten (3-12) known cycloartanetype triterpene glycosides. Structures of the new compounds were established as 3-O-beta-D-xylopyranosyl-6-O-beta-Dglucopyranosyl- 16-O-beta-D-glucopyranosyl-3 beta, 6a, 16 beta, 24(S)-25-pentahydroxycycloartane (1), 3-O-[a-L-arabinopyranosyl-(1. 2)-beta-D-xylopyranosyl]-6-O-beta-D-glucopyranosyl-16-O-beta-D-glucopyranosyl-3 beta, 6 alpha, 16 beta, 24(S)-25-pentahydroxycycloartane (2), by using 1D and 2D-NMR techniques and mass spectrometry.