Gingival crevicular fluid matrix metalloproteinase (MMP)-7, extracellular MMP inducer, and tissue inhibitor of MMP-1 levels in periodontal disease


Emingil G. , TERVAHARTIALA T., MANTYLA P., MAATTA M., SORSA T., Atilla G.

JOURNAL OF PERIODONTOLOGY, vol.77, no.12, pp.2040-2050, 2006 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 77 Issue: 12
  • Publication Date: 2006
  • Doi Number: 10.1902/jop.2006.060144
  • Title of Journal : JOURNAL OF PERIODONTOLOGY
  • Page Numbers: pp.2040-2050

Abstract

Background: During periodontal inflammation, matrix metalloproteinases (MMPs) are under the control of several regulatory mechanisms including the upregulation of expression by inducers and downregulation by inhibitors. Our study aimed to examine the levels and molecular forms of MMP-7, tissue inhibitor of MMP (TIMP) - 1, and extracellular matrix metalloproteinase inducer (EMMPRIN) in gingival crevicular fluid (GCF) from patients with different periodontal diseases.