Intralesional corticosteroid injection for central giant cell granuloma: A case report and review of the literature

Sezer B. B. , Koyuncu B. , GOMEL M., Gunbay T.

TURKISH JOURNAL OF PEDIATRICS, cilt.47, ss.75-81, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 47 Konu: 1
  • Basım Tarihi: 2005
  • Sayfa Sayıları: ss.75-81


Central giant cell granuloma (CGCG) is a benign intraosseous lesion of the jaws that is found predominantly in children and young adults. Although benign, it may be locally aggressive, causing extensive bone destruction, tooth displacement and root resorption. The common therapy is aggressive curettage, peripheral ostectomy or resection, which may be associated with loss of teeth and, in younger patients, loss of dental germs. A number of alternative nonsurgical approaches have been advocated in recent years for the management of CGCGs. These include intralesional corticosteroid injections, calcitonin injections and subcutaneous alpha-interferon injections.