Association between the eNOS (Glu298Asp) and the RAS genes polymorphisms and premature coronary artery disease in a Turkish population

Berdeli A. , Sekuri C., Cam F., Ercan E., Sagcan A., Tengiz I., ...More

CLINICA CHIMICA ACTA, vol.351, pp.87-94, 2005 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 351
  • Publication Date: 2005
  • Doi Number: 10.1016/j.cccn.2004.08.015
  • Title of Journal : CLINICA CHIMICA ACTA
  • Page Numbers: pp.87-94


Background: The renin-angiotensin system (RAS) and endothelial nitric oxide (NO) affect the pathogenesis of atherosclerosis and prognosis of coronary artery disease (CAD). Previous epidemiologic data suggested that genetic factors are more likely to affect young rather than old people. Our objective was to investigate the association between the polymorphisms of eNOS (Glu298Asp) and the RAS genes and premature CAD in a Turkish population.