Association between homocysteine and neopterin in healthy subjects measured by a simple HPLC-fluorometric method

TURGAN N., Habif S. , Parildar Z. , OZMEN D., Mutaf I., ERDENER D., ...More

CLINICAL BIOCHEMISTRY, vol.34, no.4, pp.271-275, 2001 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 4
  • Publication Date: 2001
  • Doi Number: 10.1016/s0009-9120(01)00226-0
  • Title of Journal : CLINICAL BIOCHEMISTRY
  • Page Numbers: pp.271-275


Objectives: Neopterin and homocysteine promote vascular smooth muscle cell proliferation through the activation of nuclear factor, B. The aim of this study was to investigate the relation between these two compounds in healthy subjects by a rapid HPLC-fluorometric method which simplifies sample pretreatment for the measurement of neopterin in serum.