Magnesium reduces calcification in bovine vascular smooth muscle cells in a dose-dependent manner

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KIRCELLI F., PETER M. E. , OK E. S. , Celenk F. G. , YILMAZ M. , STEPPAN S., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.27, ss.514-521, 2012 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1093/ndt/gfr321
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Sayfa Sayıları: ss.514-521

Özet

Vascular calcification (VC), mainly due to elevated phosphate levels, is one major problem in patients suffering from chronic kidney disease. In clinical studies, an inverse relationship between serum magnesium and VC has been reported. However, there is only few information about the influence of magnesium on calcification on a cellular level available. Therefore, we investigated the effect of magnesium on calcification induced by beta-glycerophosphate (BGP) in bovine vascular smooth muscle cells (BVSMCs).