Labeling of ornidazole with iodine-131


ASIKOGLU M. , Yurt F. , UNAK P.

JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, vol.237, pp.143-145, 1998 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Letter
  • Volume: 237
  • Publication Date: 1998
  • Doi Number: 10.1007/bf02386678
  • Title of Journal : JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY
  • Page Numbers: pp.143-145

Abstract

Ornidazole (1-(3-chloro-2-hydroxypropyl)-2-methyl-5-nitroimidazole) was labeled with iodine-131 by using iodogen method. Quality controls were performed by instant thin layer chromatography (ITLC) and electrophoresis methods. Labeling yield was 91%. Iodination was carried out by substitution of chloride by iodine-131. Structure was confirmed by H-1-NMR.