An investigation of the antimicrobial impact of drug combinations against Mycobacterium tuberculosis strains

Limoncu, MİNE; Ermertcan, ŞAFAK; Erac, BAYRI; Tasli, HÜSEYİN

doi:10.3906/sag-1007-934

An investigation of the antimicrobial impact of drug combinations against Mycobacterium tuberculosis strains

Limoncu M. , Ermertcan S. , Erac B. , Tasli H.

TURKISH JOURNAL OF MEDICAL SCIENCES, vol.41, no.4, pp.719-724, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 41 Issue: 4
Publication Date: 2011
Doi Number: 10.3906/sag-1007-934
Title of Journal : TURKISH JOURNAL OF MEDICAL SCIENCES
Page Numbers: pp.719-724

Abstract

Aim: To investigate the in vitro activity of linezolid and ofloxacin in combination with first-line antituberculosis agents (isoniazid and rifampicin) against M. tuberculosis strains. The use of combinations that include fluoroquinolones and oxazolidinone is now being considered for the treatment of resistant Mycobacterium tuberculosis strains.