An investigation of the antimicrobial impact of drug combinations against Mycobacterium tuberculosis strains

Limoncu M. , Ermertcan S. , Erac B. , Tasli H.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.41, ss.719-724, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 41 Konu: 4
  • Basım Tarihi: 2011
  • Doi Numarası: 10.3906/sag-1007-934
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayısı: ss.719-724

Özet

Aim: To investigate the in vitro activity of linezolid and ofloxacin in combination with first-line antituberculosis agents (isoniazid and rifampicin) against M. tuberculosis strains. The use of combinations that include fluoroquinolones and oxazolidinone is now being considered for the treatment of resistant Mycobacterium tuberculosis strains.