Early-Onset Acquired Myasthenia Gravis Secondary to Anti-Muscle-Specific Kinase Autoantibodies


Yilmaz S. , GÖKBEN S. , Serdaroglu G. , AKÇAY A.

JOURNAL OF CHILD NEUROLOGY, cilt.29, ss.108-110, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 29 Konu: 1
  • Basım Tarihi: 2014
  • Doi Numarası: 10.1177/0883073812467689
  • Dergi Adı: JOURNAL OF CHILD NEUROLOGY
  • Sayfa Sayıları: ss.108-110

Özet

Autoimmune myasthenia gravis is rarely seen during infancy. Similar to adults, 85% to 90% of generalized pediatric myasthenia gravis cases have acetylcholine receptor antibodies. Approximately 30% of the remaining cases have antibodies against muscle-specific kinase. Information on the clinical course, treatment alternatives, and prognosis of pediatric muscle-specific kinase antibody-positive myasthenia gravis is limited because of the small number of cases. Here, we present a 14-month-old girl with muscle-specific kinase antibody-positive myasthenia gravis as one of the youngest patients described so far in the literature.