Anti-Cancer Effects of Probiotic Lactobacillus acidophilus for Colorectal Cancer Cell Line Caco-2 through Apoptosis Induction


Isazadeh A., Hajazimian S., Shadman B., Safaei S., Bedoustani A. B. , Chavoshi R., ...More

PHARMACEUTICAL SCIENCES, vol.27, no.2, pp.262-267, 2021 (Journal Indexed in ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 27 Issue: 2
  • Publication Date: 2021
  • Doi Number: 10.34172/ps.2020.52
  • Title of Journal : PHARMACEUTICAL SCIENCES
  • Page Numbers: pp.262-267

Abstract

Background: Colorectal cancer is one of the most common cancers worldwide. Probiotics are useful and non-pathogenic microorganisms in the gastrointestinal tract, which can show anticancer activity through the induction of apoptosis. This study aimed to evaluate the anti-proliferative effects of Lactobacillus acidophilus probiotic on the Caco-2 colorectal cancer cell line.