Phyto-Niosomes: In Vitro Assessment of the Novel Nanovesicles Containing Marigold Extract


ÜN R. N. , BARLAS F. B. , Yavuz M., SELECI D. A. , SELECI M., GÜMÜŞ Z. P. , ...Daha Fazla

INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS, cilt.64, ss.927-937, 2015 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 64 Konu: 17
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1080/00914037.2015.1030663
  • Dergi Adı: INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
  • Sayfa Sayıları: ss.927-937

Özet

Herbal compounds, so-called phytoconstituents, illustrate poor absorption by living cells. Phytosomes are advanced form of herbal compounds that show higher absorption rate and bioavailability, which results better than conventional plant extracts. Niosomes, which are made of nonionic surfactants, create better chemical and stability conditions besides lipid vesicles. This study covers the preparation, characterization and cell culture applications of phyto-niosomes of Marigold extract. Before the encapsulation process, extracts of selected plants were prepared and the extract that presents best bioactivity was chosen. The resulting phyto-niosomes were characterized and their biological activities including cytotoxicity, wound healing and antioxidant activity were investigated.