Clinical evaluation of vulvar lichen sclerosus: case series

Kazandi M., Sahin C. , Terek M. C. , Cirpan T. , Oztekin K.

EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY, vol.31, no.5, pp.555-558, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 5
  • Publication Date: 2010
  • Page Numbers: pp.555-558


Introduction Vulvar lichen sclerosus is a chronic dermatitis which is located in labial, perineal and perianal areas The etiology of lichen sclerosus is multifactorial including genetic. autoimmune. hormonal and infectious aspects. Materials and Methods A retrospective analysis was carried out of the medical records of 82 patients who were suffering from pruritus vulva All patients had vulvar biopsy-proven diagnosis of lichen sclerosus Results: Sixty-six of patients (80 4%) were in the postmenopausal period and 16 patients (19 5%) were in the premenopausal phase Fifteen patients (18 2%) had thyroid disease, six had (7 3%) diabetes mellitus, five had (6 09%) asthma and five patients had (6 09%) other autoimmune diseases. Lichen sclerosus was most commonly located on the labia majora - 58 cases (70 7%) Sixty-four patients (78 04%) had used only potent corticosteroid therapy as the sole treatment Conclusion The first-line treatment is topical-potent or ultra-potent corticosteroids in the treatment of lichen sclerosis Vulvar lichen sclerosis may be associated with autoimmune and thyroid diseases