Susceptibility of extended-spectrum beta-lactamase-producing Escherichia coli urine isolates to fosfomycin, ciprofloxacin, amikacin and trimethoprim-sulfamethoxazole


PULLUKÇU H. , AYDEMİR S., TASBAKAN M. I. , cilli F. F. , TÜNGER A. , ULUSOY S.

TURKISH JOURNAL OF MEDICAL SCIENCES, cilt.38, ss.175-180, 2008 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 38 Konu: 2
  • Basım Tarihi: 2008
  • Dergi Adı: TURKISH JOURNAL OF MEDICAL SCIENCES
  • Sayfa Sayıları: ss.175-180

Özet

Aim: Urinary tract infections (UTIs) caused in particular by extended-spectrum beta-lactamase (ESBL)producing Escherichia coli strains are related with high morbidity and mortality, and treatment is quite difficult. These infections generally are treated by carbapenems, and their costs are high. We aimed in this study to investigate the susceptibilities of ESBL-producing E. coli strains isolated from urine cultures to fosfomycin, ciprofloxacin, amikacin and trimethoprim-sulfamethoxazole and to determine the general resistance profile in our region of these strains isolated from UTIs.