The treatment of high strength alkaloid industy wastewater was carried out by biological and chemical oxidation and by the appropriate combinations of them. As a biological treatment, activated sludge, and as a chemical treatment, catalytic wet air oxidation (CWAO), processes were used. In biological process, the effects of retention time (4, 6, 8 days) and air flowrate (3, 4.5 L/min) were tested and 6 days of retention time, 4.5 L/min air flowrate were decided to be appropriate operating conditions. In CWAO process, effects of temperature (140, 150, 160degreesC) and catalyst loading (0.5, 1 g/L) were tested. The optimum temperature and catalyst loading were found to be 150degreesC and 1g/L, respectively. In combined processes, biologically treated wastewater was subjected to CWAO and also chemically oxidized wastewater was subjected to the biological treatment. Combinations of both processes seemed not so effective. Biological treatment alone was sufficient.