Evaluation of MIF-173 G/C Polymorphism in Turkish Patients with Ankylosing Spondylitis


Creative Commons License

Gurel C. , Inanir A., Nural A. F. , Tekcan A., Rustemoglu A., Yigit S.

BALKAN MEDICAL JOURNAL, vol.33, pp.614-619, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33
  • Publication Date: 2016
  • Doi Number: 10.5152/balkanmedj.2016.141103
  • Title of Journal : BALKAN MEDICAL JOURNAL
  • Page Numbers: pp.614-619
  • Keywords: Ankylosing spondylitis, macrophage migration inhibitory factor, polymorphism, MIGRATION INHIBITORY FACTOR, JUVENILE IDIOPATHIC ARTHRITIS, INFLAMMATORY-BOWEL-DISEASE, FACTOR GENE POLYMORPHISMS, RHEUMATOID-ARTHRITIS, ASSOCIATION, MIF, SUSCEPTIBILITY, POPULATION, ONSET

Abstract

Background: Ankylosing spondylitis (AS) is a chronic inflammatory disease mainly affecting the spine and sacroiliac joints. Macrophage migration inhibitory (MIF) factor is a regulatory cytokine that inhibits random immune cell migration. MIF gene promoter polymorphisms play a role in the progression of several inflammatory disorders.