Gene polymorphisms of matrix metalloproteinase-2,-9 and-12 in periodontal health and severe chronic periodontitis

GUERKAN A., EMINGIL G. , SAYGAN B. H. , Atilla G. , Cinarcik S. , KOESE T., ...Daha Fazla

ARCHIVES OF ORAL BIOLOGY, cilt.53, ss.337-345, 2008 (SCI İndekslerine Giren Dergi) identifier identifier identifier


Aim: Matrix metalloproteinases (MMPs) are involved in periodontal tissue remodeling and degradation. MMP polymorphisms could alter transcription and function of these enzymes. The aim of this study was to investigate MMP-2, MMP-9 and MMP-12 gene polymorphisms in relation to susceptibility to severe chronic periodontitis (CP).