An Important Source for Cat and House Dust Mite Allergens: Day-Care Centers


Creative Commons License

GÜLBAHAR O. , KORKMAZ M. , ERDEM N., GOKMEN N. M. , SİN A. Z. , Ardeniz O. , ...Daha Fazla

TURKIYE KLINIKLERI TIP BILIMLERI DERGISI, cilt.32, ss.750-758, 2012 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 32 Konu: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.5336/medsci.2011-26355
  • Dergi Adı: TURKIYE KLINIKLERI TIP BILIMLERI DERGISI
  • Sayfa Sayıları: ss.750-758

Özet

Objective: Exposure to indoor allergens during childhood has been associated with an increased risk of sensitization. There is no data about indoor allergen levels in day-care centers in Turkey. We hypothesized that day-care centers (DC) would be relevant sources of cat and mite allergens. Material and Methods: Fifty-seven dust samples were collected from 19 DCs in Izmir, their gardens, and classrooms of the primary schools where the DCs are located in. A questionnaire about characteristics of DCs was completed. Fel d 1, Der p 1 and Der f 1 allergen levels were quantitated by enzyme-linked immunoassay. Results: Fel d 1 was detected in all, and mite allergens in 94.7% of the samples. Levels exceeding sensitization threshold level for cat and mite allergens were present in 73.7%, and 21.1% of DCs, respectively. Fel d 1 levels exceeding threshold level that might cause asthma exacerbation was detected in 21% of DCs. Fel d 1 levels in DCs and their gardens were higher than the classrooms of the same school. Der f 1 levels were identical in DCs, gardens and classrooms. Der p 1 concentration was higher in DCs with air-conditioning, than DCs without a ventilation system. Although there was no difference for Fel d 1 levels in DCs with or without carpeted floor, Fel d 1 concentrations in DCs with carpet were significantly higher than in classrooms with no carpet. Conclusion: Day-care centers in Izmir are important sources of indoor allergens that could cause sensitization or even allergic symptoms in children and their staff.