The taxonomic review of the tenebrionid genus Calyptopsis Solier, 1835 (Tenebrionidae: Tentyriini) of Turkey and Western Transcaucasia is given. Four new species and one new subspecies are described: C. capnisiformis volcanica subsp. nov. (from calderas of extinct volcanoes in Karaman and Manisa provinces), C. fouquei sp. nov. (Artvin Province), C. egecemi sp. nov. (Izmir Province), C. kaszabi sp. nov. (Bayburt Province), C. ottoi sp. nov. (Turkey: Hakkari and Van provinces; NE Iraq: Zagros Mts.). The lectotype of Calyptopsis lineimargo Reitter, 1897 is designated. The key and images for the Turkish and Western Transcaucasian species are given. In total, eleven species and one subspecies are known from Turkey, of which eight taxa are endemic for Anatolia.