Factors Associated With Persistent Increase in Level of Alanine Aminotransferase in Patients With Chronic Hepatitis B Receiving Oral Antiviral Therapy


JACOBSON I. M. , Washington M. K. , BUTI M., THOMPSON A., Afdhal N., FLISIAK R., ...More

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY, vol.15, no.7, pp.1087-0, 2017 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 7
  • Publication Date: 2017
  • Doi Number: 10.1016/j.cgh.2017.01.032
  • Title of Journal : CLINICAL GASTROENTEROLOGY AND HEPATOLOGY
  • Page Numbers: pp.1087-0

Abstract

BACKGROUND & AIMS: Despite complete suppression of viral DNA with antiviral agents, in some patients with chronic hepatitis B (CHB), serum levels of alanine aminotransferase (ALT) do not normalize. We investigated factors associated with persistent increases in ALT level in patients with CHB given long-term tenofovir disoproxil fumarate.