The role of PRP and adipose tissue-derived keratinocytes on burn wound healing in diabetic rats


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MANSOUB N. H. , GÜRDAL M., KARADADAŞ E. , Kabadayi H., Vatansever S., ERCAN G.

BIOIMPACTS, cilt.8, ss.5-12, 2018 (ESCI İndekslerine Giren Dergi)

  • Cilt numarası: 8 Konu: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.15171/bi.2018.02
  • Dergi Adı: BIOIMPACTS
  • Sayfa Sayısı: ss.5-12

Özet

Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients. The aim of this study was to investigate the use of platelet rich-plasma (PRP) and/or keratinocyte-like cells (KLCs) in diabetic thermal wound rat model and to evaluate EGF, FGF-2, TGF-beta 1, COL1 alpha 2, MCP-1 and VEGF-alpha as wound healing markers at the gene expression level.