The role of PRP and adipose tissue-derived keratinocytes on burn wound healing in diabetic rats


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MANSOUB N. H. , GÜRDAL M., KARADADAŞ E. , Kabadayi H., Vatansever S., ERCAN G.

BIOIMPACTS, vol.8, no.1, pp.5-12, 2018 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 8 Issue: 1
  • Publication Date: 2018
  • Doi Number: 10.15171/bi.2018.02
  • Title of Journal : BIOIMPACTS
  • Page Numbers: pp.5-12

Abstract

Introduction: Diabetic burn wounds and ulcers are significant complications of diabetic patients. The aim of this study was to investigate the use of platelet rich-plasma (PRP) and/or keratinocyte-like cells (KLCs) in diabetic thermal wound rat model and to evaluate EGF, FGF-2, TGF-beta 1, COL1 alpha 2, MCP-1 and VEGF-alpha as wound healing markers at the gene expression level.