Association of FAS-670A/G and FASL-843C/T Gene Polymorphisms on Allograft Nephropathy in Pediatric Renal Transplant Patients


Ertan P., Mir S., Ozkayin N., BERDELİ A.

IRANIAN JOURNAL OF PEDIATRICS, vol.20, no.4, pp.442-450, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 4
  • Publication Date: 2010
  • Title of Journal : IRANIAN JOURNAL OF PEDIATRICS
  • Page Numbers: pp.442-450
  • Keywords: Renal transplantation, FAS ligand, Genetic polymorphism, Genotype, TNFRSF6 FAS GENE, PROMOTER REGION, ACUTE REJECTION, MEDIATED APOPTOSIS, MESSENGER-RNA, LIGAND, EXPRESSION, DIAGNOSIS, IDENTIFICATION, LYMPHOCYTES

Abstract

Objective: FAS and FASL polymorphisms are suggested to play an important role in tubulitis that is a major component of acute rejection. The aim of this study was to investigate the role of FAS-670A/G and FASL-843C/T gene polymorphisms on allograft nephropathy in pediatric renal transplant patients