Antimicrobial Activity of TiO2-coated Orthodontic Ceramic Brackets against Streptococcus mutans and Candida albicans

Ozyildiz E., Guden M., Uzel A. , Karaboz I., Akil O., Bulut H.

BIOTECHNOLOGY AND BIOPROCESS ENGINEERING, vol.15, no.4, pp.680-685, 2010 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2010
  • Doi Number: 10.1007/s12257-009-3005-4
  • Page Numbers: pp.680-685
  • Keywords: TiO2, orthodontic brackets, antimicrobial activity, Streptococcus mutans, Candida albicans, TITANIUM-DIOXIDE, SURFACE, DISINFECTION, BACTERIA


Polycrystalline alumina ceramic orthodontic brackets were coated with anatase TiO2 film via a sol-gel dip-coating method. The surface structure morphology and composition of the films were evaluated via scanning electron microscopy, atomic force microscopy, and X-ray diffraction. The antimicrobial activity of the ceramic brackets was assessed against two oral pathogens, S. mutans and C. albicans. The results demonstrated that TiO2-coated brackets exposed to low energy UV-A illumination efficiently reduced the populations of test microorganisms relative to the uncoated brackets. The reduction efficiencies were 98% for S. mutans ATCC 10449 and 93% for C. albicans ATCC 60193.