JOURNAL OF ORGANIC CHEMISTRY, vol.83, no.5, pp.2875-2881, 2018 (Journal Indexed in SCI)
A highly effective and green procedure for the formation of alpha-alkylated ketones has been disclosed via the reaction of primary alcohols with secondary alcohols and ketones by using [IrCl(COD)(NHC)] complexes as a catalyst. Various alpha-alkylated ketones were obtained in high yields from the alkylation of alcohol with alcohol and ketone with alcohol through a borrowing hydrogen reaction by using 0.05-0.5 mol % iridium(I) and a catalytic amount of KOH (5-10 mol %) as the base under air atmosphere and within very short reaction times.