Clinically additive effect between doxazosin and amlodipine in the treatment of essential hypertension


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Nalbantgil S., Nalbantgil I., Onder R.

AMERICAN JOURNAL OF HYPERTENSION, cilt.13, ss.921-926, 2000 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 13 Konu: 8
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1016/s0895-7061(99)00279-4
  • Dergi Adı: AMERICAN JOURNAL OF HYPERTENSION
  • Sayfa Sayıları: ss.921-926

Özet

The Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure has reported that combinations of low doses of antihypertensive agents from different classes may provide additional antihypertensive efficacy and minimize the likelihood of dose-dependent adverse effects. Doxazosin and amlodipine, alone and in combination, were compared for efficacy in reducing blood pressure (BP) in 75 patients with predominantly moderate (Stage 2) hypertension.