Monoclonal antibodies in cancer immunotherapy


KİMİZ-GEBOLOGLU I., GULCE-IZ S. , Biray-Avci C.

MOLECULAR BIOLOGY REPORTS, vol.45, no.6, pp.2935-2940, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 45 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.1007/s11033-018-4427-x
  • Title of Journal : MOLECULAR BIOLOGY REPORTS
  • Page Numbers: pp.2935-2940

Abstract

Nowadays, in cancer treatments, immunotherapy which can be classified as a cancer type specific therapy is more popular than non-specific therapy methods such as surgery, radiotherapy and chemotherapy. The main aim of immunotherapy is to enable patients' immune system to target cancer cells and destroy them. The mainly used treatment methods in cancer immunotherapy are cancer vaccines, adoptive cell therapy, cytokines and monoclonal antibodies. In this review, we discuss the immunotherapy approaches, especially monoclonal antibodies which are mostly used in cancer immunotherapy in clinical applications.