The Protective Effect of Losartan on Diabetic Neuropathy in a Diabetic Rat Model


ÇAVUŞOĞLU T. , KARADENIZ T., CAGILTAY E., KARADENIZ M., YIGITTURK G., ACIKGOZ E. , ...Daha Fazla

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, cilt.123, ss.479-484, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 123 Konu: 8
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1055/s-0035-1550019
  • Dergi Adı: EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Sayfa Sayıları: ss.479-484

Özet

Aim: Involvement of the peripheral and autonomic nervous systems is possibly the most frequent complication of diabetes. Important risk factors included hyperglycemia, dyslipidemia, hypertension, and smoking. Angiotensin-converting-enzyme inhibitor (ACE) inhibitors should be beneficial in all vascular beds, including neuropathy and retinopathy. In this study we aimed to evaluate the effect of the angiotensin receptor blocker losartan on diabetic neuropathy in a diabetic rat model.