Caffeic acid phenethyl ester triggers apoptosis through induction of loss of mitochondrial membrane potential in CCRF-CEM cells


Avci C. B. , GÜNDÜZ C. , Baran Y., ŞAHİN F. , Yilmaz S. , DOĞAN Z. O. , et al.

JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY, cilt.137, ss.41-47, 2011 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 137 Konu: 1
  • Basım Tarihi: 2011
  • Doi Numarası: 10.1007/s00432-010-0857-0
  • Dergi Adı: JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
  • Sayfa Sayısı: ss.41-47

Özet

CAPE (caffeic acid phenethyl ester) is one of the most valuable and investigated component of propolis which is composed by honeybees. In the current study, we aimed at examining apoptotic effects of CAPE on CCRF-CEM leukemic cells and at determining the roles of mitochondrial membrane potential (MMP) in cell death.