UroVysion fluorescence in situ hybridization (UroVysion FISH) assay for detection of bladder cancer in voided urine of Turkish patients: a preliminary study


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Dodurga Y., Avci C. B. , Yilmaz S. , Nazli O. , Cogulu O. , Cankaya T., ...More

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, vol.17, no.2, pp.156-160, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 17 Issue: 2
  • Publication Date: 2013
  • Doi Number: 10.5114/wo.2013.34619
  • Title of Journal : WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
  • Page Numbers: pp.156-160

Abstract

Bladder cancer is the fourth most common cancer in men and the fifth most common cancer worldwide. UroVysion FISH has high sensitivity and specificity for urothelial carcinoma detection. We investigated the genetic marker detected by the UroVysion FISH technique in diagnosis of Turkish bladder cancer patients and compared these results with the urine cytology and cystoscopy. Urine specimens were analyzed using UroVysion FISH probes for abnormalities in centromeric chromosomes 3, 7, and 17 and locus-specific 9p21.