UroVysion fluorescence in situ hybridization (UroVysion FISH) assay for detection of bladder cancer in voided urine of Turkish patients: a preliminary study


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Dodurga Y., Avci C. B. , Yilmaz S. , Nazli O. , Cogulu O. , Cankaya T., ...Daha Fazla

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, cilt.17, ss.156-160, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 17 Konu: 2
  • Basım Tarihi: 2013
  • Doi Numarası: 10.5114/wo.2013.34619
  • Dergi Adı: WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
  • Sayfa Sayıları: ss.156-160

Özet

Bladder cancer is the fourth most common cancer in men and the fifth most common cancer worldwide. UroVysion FISH has high sensitivity and specificity for urothelial carcinoma detection. We investigated the genetic marker detected by the UroVysion FISH technique in diagnosis of Turkish bladder cancer patients and compared these results with the urine cytology and cystoscopy. Urine specimens were analyzed using UroVysion FISH probes for abnormalities in centromeric chromosomes 3, 7, and 17 and locus-specific 9p21.