Increased Oxidative DNA Damage in Lean Normoglycemic Offspring of Type 2 Diabetic Patients


ZENGI A., ERCAN G. , Caglayan O., TAMSEL S. , KARADENIZ M., SIMSIR I. , ...More

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.119, no.8, pp.467-471, 2011 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 119 Issue: 8
  • Publication Date: 2011
  • Doi Number: 10.1055/s-0031-1275289
  • Title of Journal : EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
  • Page Numbers: pp.467-471

Abstract

Objective: Several studies have shown increased oxidative stress in patients with pre-diabetes and newly diagnosed Type 2 diabetes mellitus (T2DM). It has been proposed that oxidative stress initiates insulin resistance in genetically predisposed individuals. The aim of this study was to evaluate the markers of oxidative stress in the off spring of patients with T2DM.