Increased Oxidative DNA Damage in Lean Normoglycemic Offspring of Type 2 Diabetic Patients

ZENGI, A.; ERCAN, GÜLİNNAZ; Caglayan, O.; TAMSEL, SADIK; KARADENIZ, M.; SIMSIR, ILGIN; HARMAN, E.; KAHRAMAN, C.; ORMAN, MEHMET; ÇETİNKALP, ŞEVKİ; OZGEN, G.

doi:10.1055/s-0031-1275289

Increased Oxidative DNA Damage in Lean Normoglycemic Offspring of Type 2 Diabetic Patients

ZENGI A., ERCAN G. , Caglayan O., TAMSEL S. , KARADENIZ M., SIMSIR I. , ...More

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES, vol.119, no.8, pp.467-471, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 119 Issue: 8
Publication Date: 2011
Doi Number: 10.1055/s-0031-1275289
Title of Journal : EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES
Page Numbers: pp.467-471

Abstract

Objective: Several studies have shown increased oxidative stress in patients with pre-diabetes and newly diagnosed Type 2 diabetes mellitus (T2DM). It has been proposed that oxidative stress initiates insulin resistance in genetically predisposed individuals. The aim of this study was to evaluate the markers of oxidative stress in the off spring of patients with T2DM.