Relationship between survival and erythrocyte sedimentation rate in patients operated for lung cancer


TEKNECİ A. K. , AKÇAM T. İ. , KAVURMACI Ö. , ÖZDİL A. , TURHAN K. , ÇAKAN A. , ...More

TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2022 (Journal Indexed in SCI) identifier

  • Publication Type: Article / Article
  • Publication Date: 2022
  • Doi Number: 10.5606/tgkdc.dergisi.2022.21217
  • Title of Journal : TURK GOGUS KALP DAMAR CERRAHISI DERGISI-TURKISH JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
  • Keywords: Erythrocyte sedimentation rate, lung cancer, postoperative survival

Abstract

Background: This study aims to investigate the relationship between preoperative erythrocyte sedimentation rate and survival in patients undergoing pulmonary resection due to lung cancer. Methods: Between January 2011 and July 2017, a total of 575 patients (433 males, 142 females; mean age: 61.2 +/- 9.9 years; range, 29 to 82 years) who were operated due to primary lung cancer in our clinic were retrospectively analyzed. The patients were grouped according to erythrocyte sedimentation rate to analyze the relationship between erythrocyte sedimentation rate and survival. Results: The mean overall survival time was 61.8 +/- 1.7 months in 393 patients with an erythrocyte sedimentation rate of <= 24 mm/h and 48.9 +/- 2.9 months in 182 patients with an erythrocyte sedimentation rate of >= 25 mm/h (p<0.001). Among the patients with Stage I-II disease, the mean survival time was 66.2 +/- 1.9 in patients with an erythrocyte sedimentation rate of <= 24 mm/h and 53.8 +/- 3.2 in patients with an erythrocyte sedimentation rate of >= 25 mm/h (p=0.008). The mean survival time in patients with adenocarcinoma was 62.4 +/- 2.4 months in patients with <= 24 mm/h erythrocyte sedimentation rate and 46.1 +/- 4.6 months in patients with >= 25 mm/h erythrocyte sedimentation rate (p=0.003). Conclusion: The relationship between elevated erythrocyte sedimentation rate and poor prognosis in patients with the same stage of the disease is promising for the use of erythrocyte sedimentation rate as a prognostic marker.