Octreotide lessens peritoneal injury in experimental encapsulated peritoneal sclerosis model

ERTILAV, Muhittin; HUR, Ender; Bozkurt, DEVRİM; SIPAHI, Savas; TİMUR, Ozge; SARSIK, BANU; AKCICEK, Fehmi; Duman, SONER

doi:10.1111/j.1440-1797.2011.01460.x

Octreotide lessens peritoneal injury in experimental encapsulated peritoneal sclerosis model

ERTILAV M., HUR E., Bozkurt D. , SIPAHI S., TİMUR O., SARSIK B. , ...More

NEPHROLOGY, vol.16, no.6, pp.552-557, 2011 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 16 Issue: 6
Publication Date: 2011
Doi Number: 10.1111/j.1440-1797.2011.01460.x
Title of Journal : NEPHROLOGY
Page Numbers: pp.552-557

Abstract

Aim: Encapsulated peritoneal sclerosis is characterized by neoangiogenesis and fibrosis. Octreotide, a somatostatin analogue is a well-known antifibrotic, antiproliferative and anti-angiogenic agent. The aim of the study is to evaluate the effects of octreotide in encapsulated peritoneal sclerosis-induced neoangiogenesis and fibrosis and compare the results with resting.