ARCHIVES OF ORAL BIOLOGY, vol.60, pp.134-143, 2015 (Journal Indexed in SCI)
Article / Article
Title of Journal :
ARCHIVES OF ORAL BIOLOGY
Matrix metalloproteinases, Obstructive sleep apnea syndrome, Periodontal disease, Saliva, Serum, Tissue inhibitor of matrix, metalloproteinases-1, NECROSIS-FACTOR-ALPHA, MATRIX METALLOPROTEINASES, NEUTROPHIL ELASTASE, MYELOPEROXIDASE, PATHOGENESIS, INFLAMMATION, DOXYCYCLINE, POPULATION, ACTIVATION, DISORDERS
Objectives: Despite increasing evidence for an association of obstructive sleep apnea syndrome (OSAS) and periodontal disease, the pathophysiological linking mechanisms remain unclear. This study aims to evaluate the salivary and serum matrix metalloproteinase-2, -8, -9 (MMP-2, -8, -9), tissue inhibitor of matrix metalloproteinase-1 (TIMP-1), myeloperoxidase (MPO), neutrophil elastase (NE), neutrophil gelatinase-associated lipocalin (NGAL), as well as degree of activation of MMP-2, -9 of patients with and without OSAS.