PTPN22 gene polymorphism in Takayasus arteritis


Sahin N., AKSU K. , Kamali S., Bicakcigil M., OEZBALKAN Z., Fresko I., et al.

RHEUMATOLOGY, cilt.47, ss.634-635, 2008 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 47 Konu: 5
  • Basım Tarihi: 2008
  • Doi Numarası: 10.1093/rheumatology/ken106
  • Dergi Adı: RHEUMATOLOGY
  • Sayfa Sayısı: ss.634-635

Özet

Objective. Takayasus arteritis (TA) is a chronic, rare granulomatous panarteritis of unknown aetiology involving mainly the aorta and its major branches. In this study, genetic susceptibility to TA has been investigated by screening the functional single nucleotide polymorphism (SNP) of PTPN22 gene encoding the lymphoid-specific protein tyrosine phosphatase.