Genistein-induced mir-23b expression inhibits the growth of breast cancer cells


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AVCI Ç. , SUSLUER S. , CAGLAR H. O. , BALCI T., Aygunes D. D. , Dodurga Y., ...More

WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY, vol.19, no.1, pp.32-35, 2015 (Journal Indexed in ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 19 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.5114/wo.2014.44121
  • Title of Journal : WSPOLCZESNA ONKOLOGIA-CONTEMPORARY ONCOLOGY
  • Page Numbers: pp.32-35
  • Keywords: breast cancer, genistein, miRNA, MCF-7

Abstract

Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer. This study aims to induce cellular stress by exposing genistein to determine alterations of miRNA expression profiles in MCF-7 cells.