Carbaryl-Induced Histopathologic Alterations on Testes of Levantine Frog, Pelophylax bedriagae (Anura: Ranidae)


ÇAKICI Ö.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, vol.91, no.1, pp.96-101, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 91 Issue: 1
  • Publication Date: 2013
  • Doi Number: 10.1007/s00128-013-1010-y
  • Title of Journal : BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Page Numbers: pp.96-101

Abstract

The aim of the study was to investigate for the first time histopathologic effects of carbaryl on the testes of adult frog, Pelophylax bedriagae. Frogs were exposed to carbaryl once by oral gavage in concentrations of 0.05, 0.1 and 0.2 mg/g. After 96 h, frogs were euthanized and dissected. Histopathological changes were more prominent in medium- (0.1 mg/g) and high-dose (0.2 mg/g) groups than in the low-dose (0.05 mg/g) group. In the low-dose group, shrinkage of some seminiferous tubules was observed. In the medium-dose group, an enlargement of interstitial spaces and germ cell necrosis were detected. In the high-dose group, prominent tubule deformation was determined. Germ cell necrosis in seminiferous tubules was frequently seen. In addition, congestion, hemorrhage, cellular infiltration and fibrosis were detected. According to these findings, it is clear that carbaryl affects male fertility in P. bedriagae.