Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans

Ozata, Deniz; Yu, Tianxiong; Mou, Haiwei; Gainetdinov, Ildar; Colpan, Cansu; Cecchini, Katharine; Kaymaz, YASİN; Wu, Pei-Hsuan; Fan, Kaili; Kucukural, Alper; Weng, Zhiping; Zamore, Phillip

doi:10.1038/s41559-019-1065-1

Evolutionarily conserved pachytene piRNA loci are highly divergent among modern humans

Ozata D. M. , Yu T., Mou H., Gainetdinov I., Colpan C., Cecchini K., ...More

NATURE ECOLOGY & EVOLUTION, vol.4, no.1, pp.156-182, 2020 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 4 Issue: 1
Publication Date: 2020
Doi Number: 10.1038/s41559-019-1065-1
Title of Journal : NATURE ECOLOGY & EVOLUTION
Page Numbers: pp.156-182

Abstract

By mapping piRNA genes in juvenile and adult human testes, the authors show that although synteny is conserved with other mammals, sequences are diverging rapidly even among modern humans.