Acceptorless Dehydrogenative Oxidation of Secondary Alcohols Catalysed by Cp*Ir-III-NHC Complexes


Gulcemal S. , Gulcemal D. , Whitehead G. F. S. , Xiao J.

CHEMISTRY-A EUROPEAN JOURNAL, cilt.22, ss.10513-10522, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 22 Konu: 30
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/chem.201601648
  • Dergi Adı: CHEMISTRY-A EUROPEAN JOURNAL
  • Sayfa Sayıları: ss.10513-10522

Özet

A series of new Ir-III complexes with carbene ligands that contain a range of benzyl wingtip groups have been prepared and fully characterised by NMR spectroscopy, HRMS, elemental analysis and X-ray diffraction. All the complexes were active in the acceptorless dehydrogenation of alcohol substrates in 2,2,2-trifluoroethanol to give the corresponding carbonyl compounds. The most active complex bore an electron-rich carbene ligand; this complex was used to catalyse the highly efficient and chemoselective dehydrogenation of a wide range of secondary alcohols to their respective ketones, with turnover numbers up to 1660. Mechanistic studies suggested that the turnover of the dehydrogenation reaction is limited by the H-2-formation step.