Impact of aging on TREM-1 responses in the periodontium: a cross-sectional study in an elderly population


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Ozturk V. O. , Belibasakis G. N. , EMİNGİL G. , Bostanci N.

BMC INFECTIOUS DISEASES, cilt.16, 2016 (SCI İndekslerine Giren Dergi) identifier identifier identifier

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Background: Aging is associated with altered immune response, which increases susceptibility to infections. sTREM-1 is involved in the amplification of the inflammatory response to bacterial infection. The present cross-sectional study aims to investigate local sTREM-1 levels in gingival crevicular fluid (GCF) as well as key periodontal pathogen levels in the subgingival plaque in an elderly cohort with periodontal health, gingivitis, and chronic periodontitis (CP).