Molecular Subtype Distribution and Cyclooxygenase-2 Expression Situation in Inflammatory Breast Cancer


Creative Commons License

PATIR P., KARACA B., SENER A., ZEKİOĞLU O. , SAYDAM G. , SEZGİN C.

MEANDROS MEDICAL AND DENTAL JOURNAL, cilt.17, ss.54-58, 2016 (ESCI İndekslerine Giren Dergi) identifier

  • Cilt numarası: 17 Konu: 2
  • Basım Tarihi: 2016
  • Doi Numarası: 10.4274/meandros.2419
  • Dergi Adı: MEANDROS MEDICAL AND DENTAL JOURNAL
  • Sayfa Sayıları: ss.54-58

Özet

Objective: Inflammatory breast cancer (IBC) is a rare and aggressive form of locally advanced breast cancer. Currently, almost all women with IBC have lymph node involvement and approximately one-third have distant metastases. Therefore, there is still need for understanding of the molecular biology and new therapy alternatives in IBC. The purpose of this study was to determine the potential role of the cyclooxygenase-2 (COX-2) expression pattern in the aggressive and fatal course of IBC and to investigate the possibility of using COX-2 inhibitors as therapy options in the treatment of IBC.