Local Atherosclerotic Plaques Are a Source of Prognostic Biomarkers for Adverse Cardiovascular Events


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DE KLEIJN D. P. V. , MOLL F. L. , HELLINGS W. E. , Ozsarlak-Sozer G. , DE BRUIN P., DOEVENDANS P. A. , ...More

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, vol.30, no.3, pp.612-0, 2010 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 3
  • Publication Date: 2010
  • Doi Number: 10.1161/atvbaha.109.194944
  • Title of Journal : ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
  • Page Numbers: pp.612-0
  • Keywords: arterectomy, atherosclerosis, biomarker, plaque, PLASMA OSTEOPONTIN LEVELS, ACUTE CORONARY SYNDROMES, CAROTID-ARTERY STENOSIS, MYOCARDIAL-INFARCTION, RISK-FACTORS, DISEASE, MICE, RUPTURE

Abstract

Objective-Atherosclerotic cardiovascular disease is a major burden to health care. Because atherosclerosis is considered a systemic disease, we hypothesized that one single atherosclerotic plaque contains ample molecular information that predicts future cardiovascular events in all vascular territories.