Gingival Crevicular Fluid, Serum Levels of Receptor Activator of Nuclear Factor-kappa B Ligand, Osteoprotegerin, and Interleukin-17 in Patients With Rheumatoid Arthritis and Osteoporosis and With Periodontal Disease

Gumus P. , Budunelı E. , Bıyıkoglu B., Aksu K. , Sarac F. , Nile C., ...More

JOURNAL OF PERIODONTOLOGY, vol.84, no.11, pp.1627-1637, 2013 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 84 Issue: 11
  • Publication Date: 2013
  • Doi Number: 10.1902/jop.2013.120595
  • Page Numbers: pp.1627-1637
  • Keywords: Gingival crevicular fluid, interleukin-17, osteoporosis, osteoprotegerin, RANK ligand, rheumatoid arthritis, CLINICAL ATTACHMENT LOSS, OSTEOCLAST DIFFERENTIATION, BONE EROSION, CELLS, INFLAMMATION, IL-17, EXPRESSION, CYTOKINE, RANKL, SYNOVIOCYTES


Background: This study is performed to evaluate gingival crevicular fluid (GCF) and serum levels of soluble receptor activator of nuclear factor-kappa B ligand (sRANKL), interleukin (IL)-17A, IL-17E, IL-17F, IL-17A/F, and osteoprotegerin (OPG) in women with rheumatoid arthritis (RA), osteoporosis (OPR), and those who are systemically healthy (SH), all with periodontal disease.