Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study


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Tengiz I., Ercan E., Aliyev E., Sekuri C., Duman C., Altuglu I.

CURRENT CONTROLLED TRIALS IN CARDIOVASCULAR MEDICINE, cilt.5, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 5
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1186/1468-6708-5-10
  • Dergi Adı: CURRENT CONTROLLED TRIALS IN CARDIOVASCULAR MEDICINE

Özet

Background: Matrix metalloproteinases ( MMPs) have been implicated in the pathogenesis of arterial aneurysms through increased proteolysis of extracellular matrix proteins. Increased proteolysis due to elevated matrix degrading enzyme activity in the arterial wall may act as a susceptibility factor for the development of coronary aneurysms. The aim of this study was to investigate the association between MMPs and presence of coronary aneurysms.