Triterpene saponins from Nigella sativa L.

Taskin M., Caliskan Ö. , Anil H., Abou-Gazar H., Khan I., Bedir E.

TURKISH JOURNAL OF CHEMISTRY, cilt.29, ss.561-569, 2005 (SCI İndekslerine Giren Dergi)

  • Cilt numarası: 29 Konu: 5
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH JOURNAL OF CHEMISTRY
  • Sayfa Sayısı: ss.561-569

Özet

Three known triterpene glycosides were isolated from the MeOH extract of dried and powdered seeds of Nigella sativa. The structures of the compounds were established as 3-O-[beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-hederagenin (1), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-28-O-[alpha-L-rhamnopyranosyl-(1 -> 4)-beta-D-glucopyranosyl-(1 -> 6)-beta-D-glucopyranosyl]-hederagenin (2), and 3-O-[beta-D-xylopyranosyl-(1 -> 3)-alpha-L-rhamnopyranosyl-(1 -> 2)-alpha-L-arabinopyranosyl]-hederagenin (3) by means of chemical and spectral methods. Compound 2 was isolated for the first time from the genus Nigella.