This study is dealing with two aspect of Serpus Han, which is located in Beyoglu district of Istanbul. The first of these is that architectural features, including the plan features of the building and decorative elements of the facade. The second one is ellipse and rectangular ceiling paintings that situated in the mirror part of the vaults on the ceiling of the two rooms on the first floor. 1148 H (1735-36 A.D.) date is given in the inscription of a window on the first floor of the building, which was processed with plaster in the arch mirror. Han was built a order stone and two order of bricks in alternatively. The building is three floors including ground and two floors. Han this feature with is one of the with rare buildings built in the 18th century. It has a rectangular plan on the ground level and U plan on the first and second floors. There is a small area which can be considered a courtyard which bounded by a wall the ground floor level. There is in a staircase leading up to the upper floors in this area. On the first and second floors of the building, the U-shaped, pointed arch, and the porch that opens into the courtyard surrounds the building. There are miter-type protrusions on the facades of the building, while alternating or brick decoration imitation plaster applications are seen on the facades. In this study, the Han is re-evaluated based on the information obtained from various sources and the data.