Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia

Eroglu, FATMA; VARDARLI, ASLI; Duzgun, ZEKERİYA; GÜNDÜZ, CUMHUR; CETINTAS, VİLDAN; KAYIKCIOGLU, LATİFE

doi:10.14744/anatoljcardiol.2018.86648

Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia

Eroglu Z. , VARDARLI A. , Duzgun Z. , GÜNDÜZ C. , CETINTAS V. , KAYIKCIOGLU M.

ANATOLIAN JOURNAL OF CARDIOLOGY, vol.19, no.5, pp.334-340, 2018 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 19 Issue: 5
Publication Date: 2018
Doi Number: 10.14744/anatoljcardiol.2018.86648
Title of Journal : ANATOLIAN JOURNAL OF CARDIOLOGY
Page Numbers: pp.334-340

Abstract

Objective: The aim of this study was to investigate the relationships between F216L (rs28942112), R496W (rs374603772), S127R (rs28942111), and D374Y (rs137852912) PCSK9 gain-of-function (GOF) mutations and primary dyslipidemia and serum lipid levels in patients with primary dyslipidemia.