Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia


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Eroglu Z. , VARDARLI A. , Duzgun Z. , GÜNDÜZ C. , CETINTAS V. , KAYIKCIOGLU M.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.19, ss.334-340, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 19 Konu: 5
  • Basım Tarihi: 2018
  • Doi Numarası: 10.14744/anatoljcardiol.2018.86648
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Sayfa Sayıları: ss.334-340

Özet

Objective: The aim of this study was to investigate the relationships between F216L (rs28942112), R496W (rs374603772), S127R (rs28942111), and D374Y (rs137852912) PCSK9 gain-of-function (GOF) mutations and primary dyslipidemia and serum lipid levels in patients with primary dyslipidemia.