Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia

Eroglu, FATMA; VARDARLI, ASLI; Duzgun, ZEKERİYA; GÜNDÜZ, CUMHUR; CETINTAS, VİLDAN; KAYIKCIOGLU, Meral

doi:10.14744/anatoljcardiol.2018.86648

Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia

Atıf İçin Kopyala

Eroglu Z. , VARDARLI A. , Duzgun Z. , GÜNDÜZ C. , CETINTAS V. , KAYIKCIOGLU M.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.19, ss.334-340, 2018 (SCI İndekslerine Giren Dergi)

Cilt numarası: 19 Konu: 5
Basım Tarihi: 2018
Doi Numarası: 10.14744/anatoljcardiol.2018.86648
Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
Sayfa Sayıları: ss.334-340

Özet

Objective: The aim of this study was to investigate the relationships between F216L (rs28942112), R496W (rs374603772), S127R (rs28942111), and D374Y (rs137852912) PCSK9 gain-of-function (GOF) mutations and primary dyslipidemia and serum lipid levels in patients with primary dyslipidemia.