GC-MS Investigation of Amaryllidaceae Alkaloids in Galanthus xvalentinei nothosubsp subplicatus

Sarikaya B. B. , BERKOV S., BASTIDA J., Kaya G. İ. , Onur M. A. , Somer N. U.

NATURAL PRODUCT COMMUNICATIONS, cilt.8, ss.327-328, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 8 Konu: 3
  • Basım Tarihi: 2013
  • Sayfa Sayıları: ss.327-328


A GC-MS analysis of alkaloids in the aerial parts and bulbs of Galanthus xvalentinei nothosubsp. subplicatus was performed for the first time. Totally, twenty-six alkaloids were identified, of which tazettine and galanthindole were the major ones. Acetylcholinesterase inhibitory activity of the alkaloidal extracts was determined using modified in vitro Ellman's method. Significant anticholinesterase activity was observed in the tested samples (bulbs: IC50 = 21.3 mu g/mL, aerial parts: IC50 = 16.3 mu g/mL).