Treatment of Intractable Midbrain Tremor with a Pedinculopontine Nucleus Radiofrequency Lesion

Akay A., Ruksen M., ULUDAĞ B. , Islekel S.

TURKISH NEUROSURGERY, vol.31, no.6, pp.989-991, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 6
  • Publication Date: 2021
  • Doi Number: 10.5137/1019-5149.jtn.34163-21.2
  • Title of Journal : TURKISH NEUROSURGERY
  • Page Numbers: pp.989-991
  • Keywords: Midbrain tremor, Pedinculopontine nucleus, Radiofrequency thermocoagulation lesion, DEEP BRAIN-STIMULATION, PEDUNCULOPONTINE NUCLEUS, SQUIRREL-MONKEY, PROJECTIONS


In this report, we present the case of a 21-year-old female with midbrain tremor involving atypical features, treated using a pedinculopontine nucleus lesion. Different targets for the treatment of midbrain tremor using radiofrequency lesion have been reported. In this case, stimulation of the thalamic ventralis intermedius nucleus and subthalamic nucleus produced no satisfactory improvement in tremor frequency and amplitude. A third goal was to obtain a significant response in terms of these outcomes with pedinculopontine nucleus stimulation.